Gene Ontology (GO) terms that are more enriched in down-regulated genes are under-represented terms? #516
Franelizabethgalvez
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I have performed enrichment analysis for up- and down-regulated gene sets with the topGO library based on GO annotations.
In writing up these results, I have questions such as: is it OK to describe the more enriched GO terms (higher number of significant annotated genes) of the up-regulated genes as over-represented, and conversely, is it OK to describe the more enriched GO terms of the down-regulated gene sets as under-represented or under-enriched?
Any clarification is helpful.
Thank you!!
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