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Is Pore-C data available? #807

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shin0727 opened this issue Apr 22, 2025 · 2 comments
Open

Is Pore-C data available? #807

shin0727 opened this issue Apr 22, 2025 · 2 comments

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@shin0727
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Hello,

I am a student conducting research in genome assembly.

I currently have the following data types for a single sample:

  1. HiFi reads
    2.ONT (Oxford Nanopore) reads
  2. Pore-C data

While reviewing the options available in hifiasm, I noticed that ONT data can be used as input. However, it seems there is no direct option to input Pore-C data for scaffolding. That said, I found that hifiasm supports Hi-C data as input for scaffolding purposes.

Given this, I would like to ask:

  1. Would it be possible to use Pore-C data in place of Hi-C data in hifiasm for scaffolding?
  2. If not, could you kindly recommend any tools or pipelines that support scaffolding using Pore-C data?

Thank you very much for your time and guidance.

@HaxyMoly
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Try Verkko

@chhylp123
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You can try Verkko first. But we will be very likely to have a new version that can perform hybrid assembly in a different way. Theoretically it will give you better results.

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