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Scripts to design primers for bisulfate-converted DNA template (Single Molecule Footprinting experiment)

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smf_primers

Script to design primers for a bisulfate-converted DNA template (Single Molecule Footprinting experiment)

  • Used to get the best possible primer pair for a given DHS region with our favorite TF binding motif
  • Indicates if "GC" present in the motif
  • Takes into account 3' end GC presence
  • Makes primers with "Y" to increase chances of amplifying templates with incomplete bisulfate conversion
  • Tm parameters optimized for NEB Q5

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Scripts to design primers for bisulfate-converted DNA template (Single Molecule Footprinting experiment)

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