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1.5.3

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@susannasiebert susannasiebert released this 25 Oct 14:39
· 1853 commits to master since this release

This is a hotfix release. It fixes the following issues:

  • pVACbind would previously throw an error if a peptide sequence in the input fasta was shorter than one of the chosen epitope lengths. This issue has been fixed by first parsing the input fasta and creating individual fasta files for each epitope length that enforce a minimum length of the peptide sequences matching the respective epitope length.
  • Previous versions of pVACtools resolved an issue where IEDB would output a warning line if one of the epitope sequences only contained A, C, G, or T amino acids, since those sequences could also be nuclotide sequences. However, this issue was only fixed in pVACseq, not pVACbind, or pVACvector. This release fixes this issue for all tools.
  • The wrappers for NetChop or NetMHCstabpan split the set of input epitopes into chunks of 100 before processing. Due to a bug in the file splitting logic, one epitope for each chunk over 100 would be errenously dropped. This effectively would result in less epitopes being returned in the filtered report than if running the pipelines without NetChop or NetMHCstabpan.